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Computational Model of Secondary Palate Fusion and Disruption ChemResTox Data
Morphogenetic events are driven by cell-generated physical forces and complex cellular dynamics. To improve our capacity to predict developmental effects from cellular... -
TZurlinden_pluripotent human (H9) embryonic stem cell
The data presented here support the application of the Stemina devTOXqP platform for predictive toxicology and further demonstrate its value in ToxCast as a novel resource that... -
Characterizing cleft palate toxicants using ToxCast data, chemical...
A data set of 500 chemicals evaluated for their ability to induce cleft palate in animal prenatal developmental studies was compiled from Toxicity Reference Database and the... -
Estimating Hepatotoxic Doses Using High-content Imaging in Primary Hepatocytes
This repository contains the necessary data, python source code and jupyter notebooks to reproduce the results from our manuscript, "Estimating Hepatotoxic Doses Using High-... -
A cross-platform approach to characterize and screen potential neurovascular...
Development of the neurovascular unit (NVU) is a complex, multistage process that requires orchestrated cell signaling mechanisms across several cell types and ultimately... -
Computational Modeling and Simulation of Genital Tubercle Development
Hypospadias is a developmental defect of urethral tube closure that has a complex etiology involving genetic and environmental factors, including anti-androgenic and estrogenic...