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Empirical characterization of the expression ratio noise structure in high-de...
Background High-density oligonucleotide arrays (HDONAs) are a powerful tool for assessing differential mRNA expression levels. To establish the statistical significance of an... -
Expression profiles during honeybee caste determination
Background Depending on their larval environment, female honeybees develop into either queens or workers. As in other polyphenisms, this developmental switch depends not on... -
Advanced analysis of a
Background Previously, we reported effects of the cryb mutation on circadian rhythms in period and timeless gene expression within isolated peripheral Drosophila tissues. We... -
Poly purine.pyrimidine sequences upstream of the beta-galactosidase gene affe...
Background Poly purine.pyrimidine sequences have the potential to adopt intramolecular triplex structures and are overrepresented upstream of genes in eukaryotes. These... -
Evidence for large domains of similarly expressed genes in the
Background Transcriptional regulation in eukaryotes generally operates at the level of individual genes. Regulation of sets of adjacent genes by mechanisms operating at the... -
Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal ...
Background Members of the ribonuclease III superfamily of double-stranded(ds)-RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in... -
The major transcription initiation site of the
Background The cyclin-dependent kinase inhibitor p27Kip1 is essential for proper control of cell cycle progression. The levels of p27Kip1 are regulated by several mechanisms... -
ESR1 expression and DNA methylation data for FHM exposed to EE2
This dataset contains data for adult male fathead minnows exposed to EE2 (a synthetic estrogen). It is a targeted study on the response of the esr1 gene (expression and DNA... -
Evolutionary conservation of
Background Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that the... -
Heat shock protein gene expression and survival in critical illness
Heat shock protein gene expression and survival in critical illness -
Vector algebra in the analysis of genome-wide expression data
Background Data from thousands of transcription-profiling experiments in organisms ranging from yeast to humans are now publicly available. How best to analyze these data... -
Analysis of strain and regional variation in gene expression in mouse brain
Background We performed a statistical analysis of a previously published set of gene expression microarray data from six different brain regions in two mouse strains. In the... -
Gene expression in epithelial cells in response to pneumovirus infection
Respiratory syncytial virus (RSV) and pneumonia virus of mice (PVM) are viruses of the family Paramyxoviridae, subfamily pneumovirus, which cause clinically important... -
Design and implementation of microarray gene expression markup language (MAGE...
Meaningful exchange of microarray data is currently difficult because it is rare that published data provide sufficient information depth or are even in the same format from one... -
Research Article: BMC Genomics
Background Gonadotropin releasing hormone (GnRH) is responsible for stimulation of gonadotropic hormone (GtH) in the hypothalamus-pituitary-gonadal axis (HPG). The regulatory... -
Efficacy of SSH PCR in isolating differentially expressed genes
Background Suppression Subtractive Hybridization PCR (SSH PCR) is a sophisticated cDNA subtraction method to enrich and isolate differentially expressed genes. Despite its... -
Computational prediction of membrane-tethered transcription factors
Background Sequestration of transcription factors in the membrane is emerging as an important mechanism for the regulation of gene expression. A handful of membrane-spanning... -
Differential expression of Aquaporin 8 in human colonic epithelial cells and ...
Background The gene expression pattern in tumor cells differs from that in corresponding normal cells. In order to identify differentially expressed genes in colorectal tumors... -
The cloning, genomic organization and tissue expression profile of the human ...
Background Familial atrial fibrillation, an autosomal dominant disease, was previously mapped to chromosome 10q22. One of the genes mapped to the 10q22 region is DLG5, a member... -
Acute Ozone-Induced Transcriptional Changes in Markers of Oxidative Stress an...
The dataset is comprised of multiple data-frames. Our focus is on sex and brain region specific responses to ozone in a rat model. The PCR data describes the gene expression...