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Activation of the Fas/Fas ligand pathway in hypertensive renal disease in Dah...
Background Hypertensive nephrosclerosis is the second most common cause of end-stage renal failure in the United States. The mechanism by which hypertension produces renal... -
Patterns in abundance and diversity of faecally dispersed parasites of tiger ...
Background Importance of parasites in ecological and evolutionary interactions is being increasingly recognized. However, ecological data on parasites of important host species... -
Oral sildenafil (Viagra™) in male erectile dysfunction: use, efficacy and saf...
Introduction Sildenafil (Viagra®) is one of the drugs used in the first line therapy of male erectile dysfunction (MED). We have recorded outcomes, adverse events and... -
Apoptosis and p53 expression in rat adjuvant arthritis
The kinetics of apoptosis and the apoptosis-regulating gene p53 in adjuvant arthritis (AA) were investigated to assess the value of the AA rat model for testing apoptosis-... -
Debate: Should statin be used in patients with heart failure?
Statins reduce mortality of patients with coronary artery disease (CAD). However, by protocol, trials have excluded patients with chronic heart failure. Since the prevalent... -
A basis for a visual language for describing, archiving and analyzing functio...
Background: We propose that a computerized, internet-based graphical description language for systems biology will be essential for describing, archiving and analyzing complex... -
The human Y chromosome: the biological role of a “functional wasteland”
“Functional wasteland,” “Nonrecombining desert,” and “Gene-poor chromosome” are only some examples of the different definitions given to the Y chromosome in the last decade. In... -
Cisapride decreases gastric content aspiration in mechanically ventilated...
Objective: To determine the effect of the prokinetic agent cisapride in the prevention of aspiration of gastric contents. Design: A prospective randomized two-period crossover... -
The
Background The frizzled pathway in Drosophila has been studied intensively for its role in the development of planar polarity in wing hairs, thoracic bristles and ommatidia.... -
Effect of a homeopathic drug, Chelidonium, in amelioration of p-DAB induced h...
Background Crude extracts of Chelidonium majus, and also purified compounds derived from crude extracts of this plant, have been reported to exhibit anti-viral, anti-... -
Coordinate regulation of RARgamma2, TBP, and TAF
Background Treatment of mouse F9 embryonal carcinoma cells with all-trans retinoic acid (T-RA) induces differentiation into primitive endodermal type cells. Differentiation... -
Bouveret's syndrome complicated by distal gallstone ileus after laser lithotr...
Background Bouveret's syndrome is an unusual presentation of duodenal obstruction caused by the passage of a large gallstone through a cholecystoduodenal fistula. Endoscopic... -
New insights into the effects on blood pressure of diets low in salt and high...
Results from the recent Dietary Approaches to Stop Hypertension (DASH)-Sodium trial provide the latest evidence concerning the effects of dietary patterns and sodium intake on... -
Identification of conserved C2H2 zinc-finger gene families in the Bilateria
Background: Identification of orthologous relationships between genes from widely divergent taxa allows partial reconstruction of the gene complement of ancestral genomes. C2H2... -
Circulating cytotoxic CD8
Circulating CD8+ CD28- T cells were found to be expanded more in patients with ankylosing spondylitis than in an age-matched healthy population (41.2 ± 17.7% versus 18.6 ±... -
Parallel evolution of histophagy in ciliates of the genus
Background Species of Tetrahymena were grouped into three complexes based on morphological and life history traits: the pyriformis complex of microstomatous forms; the patula... -
Effects of microcosm scaling and food resources on growth and survival of larval
Background We used a simple experimental design to test for the effects of microcosm scaling on the growth and survival of the mosquito, Culex pipiens. Microcosm and mesocosm... -
Antenatal screening and its possible meaning from unborn baby's perspective
In recent decades antenatal screening has become one of the most routine procedure of pregnancy-follow up and the subject of hot debate in bioethics circles. In this paper the... -
Evidence for the adaptive significance of an LTR retrotransposon sequence in a
Background The potential adaptive significance of transposable elements (TEs) to the host genomes in which they reside is a topic that has been hotly debated by molecular... -
Genetics of rheumatoid arthritis: confronting complexity
The genetic basis for rheumatoid arthritis (RA) is likely to be extremely complex. Even the role of MHC genes remains to be fully defined, and may involve interactive genetic...