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Molecular mechanism of flocculation self-recognition in yeast and its role...
Saccharomyces cerevisiae flocculation occurs when fermentable sugars are limiting and is therefore considered as a way to enhance the survival chance of Flo-expressing yeast... -
Action of microgravity on root development
Arabidopsis were grown on horizontal or vertical clinostat for 4 8 or 12 days. Seedlings on horizontal clinostat were in simulated microgravity and seedlings on vertical... -
Immediate Transcriptional Changes in Response to High Dose Radiation Exposure
One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy (HZE)... -
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential... -
Effects of spaceflight on murine skeletal muscle gene expression
Spaceflight results in a number of adaptations to skeletal muscle including atrophy and shifts towards faster muscle fiber types. To identify changes in gene expression that may... -
Candida albicans response to spaceflight (NASA STS-115)
This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen Candida albicans grown in... -
Dynamic gene expression response to altered gravity in human T cells...
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
MicroRNA expression of C. elegans in space environment
Entire microRNA expression were analyzed using the Filgen Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis we compared the expression... -
Gene expression response to simulated gravity and hypergravity in human T cells
We investigated differentially regulated and stably expressed genes in human Jurkat T lymphocytic cells in 5min simulated microgravity and hypergravity and compared expression... -
Transcription profiling of human MCF10A cells subjected to ionizing...
Transforming growth factor beta-1 (TGFbeta) is a tumor suppressor during the initial stage of tumorigenesis but it can switch to a tumor promoter during neoplastic progression.... -
Bacillus subtilis strains at low-pressure: 5 kPa versus 101 kPa growth
Comparing the transcriptional responses of Bacillus subtilis strains WN624 and WN1106 at 5 kPa and 101 kPa. WN1106 is a 5 kPa-evolved strain with increased fitness compared to... -
A Molecular Genetic Basis Explaining Altered Bacterial Behavior in Space
Bacterial behavior has been observed to change during spaceflight. Higher final cell counts enhanced biofilm formation increased virulence and reduced susceptibility to... -
Transcriptomics analysis of etiolated Arabidopsis thaliana seedlings in...
Gene expression profile of two-week-old etiolated Arabidopsis seedlings under microgravity on board space flight BRIC16 were compared with ground grown control in both wild-type... -
Exposure to ionizing radiation induced persistent gene expression changes in...
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation. RNA was... -
Spaceflight Modulates Gene Expression in Astronauts
Astronauts are exposed to a unique combination of stressors during spaceflight which leads to alterations in their physiology and potentially increases their susceptibility to... -
Gene expression in human peripheral blood 48 hours after exposure to...
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to predict... -
Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the...
Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology yet the apparent components of hypobaria are stresses typical of... -
Comparative Transcriptomic Analysis of Adult Medaka Tissues Sampled after...
To understand how humans adapt to space environments many experiments can be conducted on astronauts while they work aboard the Space Shuttle or the International Space Station... -
Transcription profiling of Arabidopsis seedings exposed to UV-B irradiation
Interaction of COP1 and UVR8 which regulate UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis thaliana. -
Alteration of Proteomes in First-generation Cultures of Bacillus pumilus...
Bacillus pumilus SAFR-032 was originally isolated from the Jet Propulsion Lab Spacecraft Assembly Facility and thoroughly characterized for its enhanced resistance to UV...