@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://data.amerigeoss.org/dataset/0d2857e0-40ad-476b-989f-37eb5836c272> a dcat:Dataset ;
    dct:description """Background
          Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data. Clustering techniques have been widely applied in analyzing microarray gene-expression data. However, normal mixture model-based cluster analysis has not been widely used for such data, although it has a solid probabilistic foundation. Here, we introduce and illustrate its use in detecting differentially expressed genes. In particular, we do not cluster gene-expression patterns but a summary statistic, the t-statistic.
        
        
          Results
          The method is applied to a data set containing expression levels of 1,176 genes of rats with and without pneumococcal middle-ear infection. Three clusters were found, two of which contain more than 95% genes with almost no altered gene-expression levels, whereas the third one has 30 genes with more or less differential gene-expression levels.
        
        
          Conclusions
          Our results indicate that model-based clustering of t-statistics (and possibly other summary statistics) can be a useful statistical tool to exploit differential gene expression for microarray data.""" ;
    dct:identifier <https://healthdata.gov/api/views/yh42-xkaf> ;
    dct:issued "2025-07-14"^^xsd:date ;
    dct:modified "2025-09-06"^^xsd:date ;
    dct:publisher <https://data.amerigeoss.org/organization/727dbdd5-3f98-4ac0-9d28-5e344558139b> ;
    dct:title "Model-based cluster analysis of microarray gene-expression data" ;
    dcat:contactPoint [ a vcard:Organization ;
            vcard:fn "NIH" ;
            vcard:hasEmail <mailto:info@nih.gov> ] ;
    dcat:distribution <https://data.amerigeoss.org/dataset/0d2857e0-40ad-476b-989f-37eb5836c272/resource/dd3d8be0-801d-49f2-83e8-af3a80134299> ;
    dcat:keyword "AmeriGEO",
        "AmeriGEOSS",
        "CKAN",
        "GEO",
        "GEOSS",
        "National",
        "North America",
        "United States",
        "cluster-analysis",
        "gene-expression",
        "microarray-data",
        "nih",
        "pneumococcal-infection" ;
    dcat:theme <%7BNIH%7D> .

<https://data.amerigeoss.org/dataset/0d2857e0-40ad-476b-989f-37eb5836c272/resource/dd3d8be0-801d-49f2-83e8-af3a80134299> a dcat:Distribution ;
    dct:description "Visit the original government dataset for complete information, documentation, and data access." ;
    dct:format "HTML" ;
    dct:issued "2025-07-24T14:05:24.640739"^^xsd:dateTime ;
    dct:modified "2025-09-23T19:27:22.302183"^^xsd:dateTime ;
    dct:title "Official Government Data Source" ;
    dcat:accessURL <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC65687/> ;
    dcat:mediaType "text/html" .

<https://data.amerigeoss.org/organization/727dbdd5-3f98-4ac0-9d28-5e344558139b> a foaf:Agent ;
    foaf:name "US Migrating" .

