Minimizing charges associated with the determination of brain death
type: Dataset
description: Background: The purpose of this study was to evaluate the effect of altering the use of the protocol for brain death determination in traumatically injured patients, on time to brain death determination, medical complication rates, organ procurement rates and charges for care rendered during brain death determination. A retrospective chart review of trauma patients with lethal brain injuries at an urban tertiary care trauma center was performed. Two groups of trauma patients with lethal head injuries were compared. Group I consisted of patients pronounced brain dead using a protocol requiring two brain examinations, and group II contained patients evaluated using a protocol requiring one brain examination in conjunction with a nuclear medicine brain flow scan. Results: Group II had a significantly (P < 0.01) shorter mean brain death stay (3.5 ± 1.8 h) than group I (12.0 ± 1.0 h). Patients in groups I and II developed a similar number of medical complications, 3.2 ± 0.2 and 4.0 ± 1.3, respectively. The number of organs procured per patient did not differ significantly (4.1 ± 0.2 for group I and 4.4 ± 1.4 for group II). There was a significant (P < 0.01) decrease in the brain death stay charges for group II ($6125 ± 1100) compared to group I ($16,645 ± 1223). Conclusions: Medical complications are universal in the traumatized patient awaiting the determination of brain death. These complications necessitate aggressive and costly care in the intensive care unit in order to optimize organ function in preparation for possible transplantation. In our institution, the determination of brain death using a single clinical examination and a nuclear medicine flow study significantly shortened the brain death stay and reduced associated charges accrued during this period. The complication and organ procurement rates were not affected in this small, preliminary report sample.
issued: 2025-07-13
modified: 2025-09-06
contact point: Organization
  fn: NIH
keyword: AmeriGEO
keyword: AmeriGEOSS
keyword: CKAN
keyword: GEO
keyword: GEOSS
keyword: National
keyword: North America
keyword: United States
keyword: brain-death-determination
keyword: cerebral-blood-flow
keyword: nih
keyword: organ-donation
keyword: traumatic-brain-injury
theme: {NIH}

Official Government Data Source
type: Distribution
description: Visit the original government dataset for complete information, documentation, and data access.
format: HTML
issued: 2025-07-24T03:44:16.424193
modified: 2025-09-24T15:41:15.479228
access URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC28989/
media type: text/html

US Migrating
type: Agent