Pervasive environmental chemicals impair oligodendrocyte development
type: Dataset
description: Data for EPA collaboration with Case Western Reserve Univ, Erin Cohn, et al. 'Pervasive environmental chemicals impair oligodendrocyte development', DOI https://doi.org/10.1038/s41593-024-01599-2. Primary screening results are available in Supplementary Table 1 and will be included in a future public release of the EPA ToxCast database. RNA-seq datasets generated in this study have been deposited in Gene Expression Omnibus (https://www.ncbi.nlm.nih.gov/geo) under accession code GSE244500. This dataset is associated with the following publication: Cohn, E., B. Clayton, M. Madhavan, K. Lee, S. Yacoub, Y. Fedorov , M. Scavuzzo, K. Paul-Friedman, T. Shafer, and P. Tesar. Pervasive environmental chemicals impair oligodendrocyte development. Nature Neuroscience. Nature Portfolio, Berlin, GERMANY, 27(5): 836-845, (2024).
issued: 2025-09-24T06:05:29.391822
modified: 2024-01-23
contact point: Organization
  fn: Katie Friedman
keyword: AmeriGEO
keyword: AmeriGEOSS
keyword: CKAN
keyword: GEO
keyword: GEOSS
keyword: National
keyword: North America
keyword: United States
keyword: cytotoxicity
keyword: neurotoxicity
keyword: oligodendrocytes
keyword: screening

https://data.amerigeoss.org/dataset/1df1a00c-30c8-4e65-a488-03863eb70a7e/resource/15699423-f075-40c9-8b90-8e3e1dcec277
type: Distribution
issued: 2024-07-28T21:54:45.786342
modified: 2025-09-24T06:05:29.359927
title: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi
access URL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi

Supplementary Table 3- Gene set enrichment analysis.xlsx
type: Distribution
description: Supplementary Table 3- Gene set enrichment analysis.xlsx
format: XLS
issued: 2024-07-28T21:54:45.786345
modified: 2025-09-24T06:05:29.363801
access URL: https://pasteur.epa.gov/uploads/10.23719/1530984/Supplementary%20Table%203-%20Gene%20set%20enrichment%20analysis.xlsx
media type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

Supplementary Table 2- ToxPrint enrichment analysis.xlsx
type: Distribution
description: Supplementary Table 2- ToxPrint enrichment analysis.xlsx
format: XLS
issued: 2024-07-28T21:54:45.786347
modified: 2025-09-24T06:05:29.365511
access URL: https://pasteur.epa.gov/uploads/10.23719/1530984/Supplementary%20Table%202-%20ToxPrint%20enrichment%20analysis.xlsx
media type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

Supplementary Table 1- Primary screening results.xlsx
type: Distribution
description: Supplementary Table 1- Primary screening results.xlsx
format: XLS
issued: 2024-07-28T21:54:45.786349
modified: 2025-09-24T06:05:29.366768
access URL: https://pasteur.epa.gov/uploads/10.23719/1530984/Supplementary%20Table%201-%20Primary%20screening%20results.xlsx
media type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

US Migrating
type: Agent