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Proton Irradiation Impacts Age Driven Modulations of Cancer Progression Influ...
Age plays a crucial role in the interplay between tumor and host; with further perturbations induced by irradiation. Proton irradiation on tumors induces biological modulations... -
Molecular mechanism of flocculation self-recognition in yeast and its role in...
Saccharomyces cerevisiae flocculation occurs when fermentable sugars are limiting and is therefore considered as a way to enhance the survival chance of Flo-expressing yeast... -
Transcriptome Profiles in Normal Human Bronchial Epithelial Cells after Expos...
Distinct transcriptome profiles in response to low-LET and high-LET and different radiation qualities of HZE particles. Total RNA obtained from HBEC3KT cells after 1 4 12 and 24... -
Immediate Transcriptional Changes in Response to High Dose Radiation Exposure
One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy (HZE)... -
Murine microenvironment metaprofiles associate with human cancer etiology and...
We developed a mouse model that captures radiation effects on host biology by transplanting unirradiated Trp53 null mammary tissue to sham or irradiated hosts. Gene expression... -
Gene expression in blood of mice with internal exposure to Cs-137
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear detonations. When ingested or inhaled it can expose the entire body for an extended period... -
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential... -
Candida albicans response to spaceflight (NASA STS-115)
This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen Candida albicans grown in... -
Worms spun in centrifuge at elevated g values
Worms spun at higher than normal g values for 4 days on 20G centrifuge vs. worms kept at 1 X G. Both are mixed stage cultures. A stimulus or stress experiment design type is... -
Expression data from drosophila melanogaster
Space travel presents unlimited opportunities for exploration and discovery but requires a more complete understanding of the immunological consequences of long-term exposure to... -
Transcription profiling of human MCF10A cells subjected to ionizing radiation...
Transforming growth factor beta-1 (TGFbeta) is a tumor suppressor during the initial stage of tumorigenesis but it can switch to a tumor promoter during neoplastic progression.... -
Gene expression profiling of human peripheral blood lymphocytes cultured in m...
In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition simulated by a ground-based... -
Bacillus subtilis strains at low-pressure: 5 kPa versus 101 kPa growth
Comparing the transcriptional responses of Bacillus subtilis strains WN624 and WN1106 at 5 kPa and 101 kPa. WN1106 is a 5 kPa-evolved strain with increased fitness compared to... -
microRNA expression profiles in human peripheral blood lymphocytes cultured i...
In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition simulated by a ground-based... -
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Id...
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy 1 GeV proton (1H) and 15 cGy 1 GeV/nucleon (n) iron... -
The Role of PTHrP in Osteoblast Response to Microgravity: Implications for Os...
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This rapid effect... -
Exposure to ionizing radiation induced persistent gene expression changes in ...
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation. RNA was... -
Spaceflight Modulates Gene Expression in Astronauts
Astronauts are exposed to a unique combination of stressors during spaceflight which leads to alterations in their physiology and potentially increases their susceptibility to... -
Gene expression in human peripheral blood 48 hours after exposure to ionizing...
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to predict... -
Exposure to ionizing radiation induced persistent gene expression changes in ...
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation. RNA was...
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