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Microbial Observatory (ISS-MO): Study of BSL-2 bacterial isolates from the In...
In an on-going Microbial Observatory experimental investigation on the International Space Station (ISS) multiple bacterial isolates of Biosafety Level 2 (BSL-2) were isolated... -
Microbial Observatory (ISS-MO): Microbial diversity
The environmental microbiome study was designed to decipher microbial diversity of the International Space Station surfaces in terms of spatial and temporal distributions using... -
Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic ...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Genetic Dissection of the Spaceflight Transcriptome Responses in Plants: are ...
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural and... -
Streptococcus mutans differential gene expression in response to simulated mi...
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host factors... -
Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic proteomic and epi...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse soleus muscle transcrip...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS...
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These baseline... -
RNA-seq analysis of mycobacteria stress response to microgravity
The aim of this work is to determine whether mycobacteria have enhanced virulence during space travel and what mechanisms they use to adapt to microgravity. M. marinum and LHM4... -
Effect of microgravity on an animal-bacteria symbiosis
Spaceflight imposes numerous adaptive challenges for terrestrial life. The reduction in gravity or microgravity represents a novel environment that can disrupt homeostasis of... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse extensor digitorum long...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Biomolecule Sequencer
Technology demonstration of a nanopore sequencer operating aboard the ISS in comparison with the same sequencer on the ground. -
Temporal dynamics of the gut microbiota in people sharing a confined environm...
The MARS500 project the longest ground-based space simulation ever provided us with a unique opportunity to trace the crew microbiota over 520 days of isolated confinement such... -
Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast Del...
Spaceflight is a unique environment with profound effects on biological systems including tissue redistribution and musculoskeletal stresses. However the more subtle biological... -
Comparison of the spaceflight transcriptome of four commonly used Arabidopsis...
This experiment compared the spaceflight transcriptomes of four commonly used natural variants (ecotypes) of Arabidopsis thaliana using RNAseq. In nature Arabidopsis is a native... -
Validation of Methods to Assess the Immunoglobulin Gene Repertoire in Tissues...
Spaceflight is known to affect immune cell populations. In particular splenic B-cell numbers decrease during spaceflight and in ground-based physiological models. Although... -
Analysis of dust samples from the Russian part of the ISS
Our study focuses on the hardiest microorganisms inhabiting the ISS in order to assess their diversity and capabilities to resist certain stresses. We specifically selected dust... -
A Molecular Genetic Basis Explaining Altered Bacterial Behavior in Space
Bacterial behavior has been observed to change during spaceflight. Higher final cell counts enhanced biofilm formation increased virulence and reduced susceptibility to... -
Adaptive changes in the vestibular system of land snail to a 30-day spaceflig...
The vestibular system receives a permanent influence from gravity and reflexively controls equilibrium. If we assume gravity has remained constant during the species evolution... -
Rodent Research-3-CASIS: Mouse retina transcriptomic data
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the...
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