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Response of the EPI-200 human 3-D skin model to high and low doses of protons
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose responses. Most... -
Effects of spaceflight on murine skeletal muscle gene expression
Spaceflight results in a number of adaptations to skeletal muscle including atrophy and shifts towards faster muscle fiber types. To identify changes in gene expression that may... -
Dynamic gene expression response to altered gravity in human T cells (soundin...
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
Gene expression response to simulated gravity and hypergravity in human T cells
We investigated differentially regulated and stably expressed genes in human Jurkat T lymphocytic cells in 5min simulated microgravity and hypergravity and compared expression... -
Proton irradiation augments the reduction in tumor progression observed with ...
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have shown that in... -
Effects of 21 days of bedrest on human skeletal muscle gene expression
The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic bedrest (NBR)... -
Effects of a Closed Space Environment on Gene Expression in Hair Follicles of...
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose... -
A Molecular Genetic Basis Explaining Altered Bacterial Behavior in Space
Bacterial behavior has been observed to change during spaceflight. Higher final cell counts enhanced biofilm formation increased virulence and reduced susceptibility to... -
Dissecting Low Atmospheric Pressure Stress: Transcriptome Responses to the Co...
Controlled hypobaria presents biology with an environment that is never encountered in terrestrial ecology yet the apparent components of hypobaria are stresses typical of... -
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) a...
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special emphasis on... -
Exposure of zebrafish larvae to 3g and 5g hyper gravity between 5-6 days post...
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason the... -
Dynamic gene expression response to altered gravity in human T cells (soundin...
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify...