Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station

In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose physiological problems to the astronauts after their return. Therefore it is important to develop healthcare technologies for astronauts. In this study hair an easy-to-obtain sample was identified as the candidate. In order to investigate the genetic changes in human hair during space flight the hair follicles of 10 astronauts were analyzed by DNA microarray and real time q-PCR analyses. Space environment induced gene expression of hair follicles of astronaut was measured 6 differnent times included 2 in flight on orbit. Ten independent experiments were performed on differing astronauts. and the sampling day was differed for each astronaut because of their schedules.

Data and Resources

Field Value
accessLevel public
accrualPeriodicity irregular
bureauCode {026:00}
catalog_@context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
catalog_@id https://data.nasa.gov/data.json
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
catalog_describedBy https://project-open-data.cio.gov/v1.1/schema/catalog.json
identifier nasa_genelab_GLDS-174
issued 2018-06-26
landingPage https://data.nasa.gov/d/wsrn-u3aw
modified 2020-01-29
programCode {026:005}
publisher National Aeronautics and Space Administration
resource-type Dataset
source_datajson_identifier true
source_hash f36002b177c5182179b59cf14219509475df2ab9
source_schema_version 1.1
theme {"Earth Science"}
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • amerigeo
  • amerigeoss
  • ckan
  • data-collection
  • exposure-duration
  • geo
  • geoss
  • labeling
  • national
  • normalization-data-transformation
  • north-america
  • nucleic-acid-hybridization
  • rna-extraction
  • sex
  • spaceflight
  • treatment-protocol
  • united-states
isopen False
license_id notspecified
license_title License not specified
maintainer GeneLab Outreach
maintainer_email genelab-outreach@lists.nasa.gov
metadata_created 2025-11-20T15:07:57.794826
metadata_modified 2025-11-20T15:07:57.794830
notes In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose physiological problems to the astronauts after their return. Therefore it is important to develop healthcare technologies for astronauts. In this study hair an easy-to-obtain sample was identified as the candidate. In order to investigate the genetic changes in human hair during space flight the hair follicles of 10 astronauts were analyzed by DNA microarray and real time q-PCR analyses. Space environment induced gene expression of hair follicles of astronaut was measured 6 differnent times included 2 in flight on orbit. Ten independent experiments were performed on differing astronauts. and the sampling day was differed for each astronaut because of their schedules.
num_resources 1
num_tags 17
title Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station