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Global gene expression analysis highlights microgravity sensitive key genes i...
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in physiological... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse kidney transcriptomic p...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Medaka Osteoclast
During space flight bone mineral density is decreased by the influence of osteoclast activation which molecular mechanism is expectantly investigated. In the study of medaka... -
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiom...
With extended stays aboard the International Space Station (ISS) becoming commonplace there is a need to better understand the effects of microgravity on cardiac function. We... -
Proton irradiation augments the reduction in tumor progression observed with ...
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have shown that in... -
Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic proteomic and epi...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic pr...
RR-1 is a validation flight to evaluate the hardware operational and science capabilities of the Rodent Research Project on the ISS. RNA DNA and protein were purified from liver... -
RNA-Seq transcriptome analysis of reactive oxygen species gene network in Miz...
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of ROS gene... -
The influence of simulated microgravity on the proteome of Daphnia magna
Background/Objectives: The waterflea Daphnia is an interesting candidate for bioregenerative life support systems (BLSS). These animals are particularly promising because of... -
Comparative gene expression analysis in the Arabidopsis thaliana root apex us...
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse... -
Streptococcus mutans differential gene expression in response to simulated mi...
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host factors... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse quadriceps muscle trans...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources...