Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic proteomic and epigenomic data

RR-1 is a validation flight to evaluate the hardware operational and science capabilities of the Rodent Research Project on the ISS. RNA DNA and protein were purified from liver tissues from RR-1 mice (female C57BL/6J 16wk old at time of launch). From each group two liver samples were collected and frozen immediately after euthanasia. The rest of the liver samples from each group were collected from frozen carcasses dissected post-flight. RNA-Seq whole genome and RNA BS-Seq (bisulfite sequencing) and proteomic expression profiling were performed. RNA extracted from these tissues was re-sequenced; these data are available as part of GLDS-168 (https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-168).

Data and Resources

Field Value
accessLevel public
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identifier nasa_genelab_GLDS-48_yu9g-2ft3
issued 2021-05-21
landingPage https://data.nasa.gov/dataset/rodent-research-1-rr1-nasa-validation-flight-mouse-liver-transcriptomic-proteomic-and-epig
license http://www.usa.gov/publicdomain/label/1.0/
modified 2025-04-23
programCode {026:005}
publisher National Aeronautics and Space Administration
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Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • 5mc-total-rna-methylation-analysis
  • AmeriGEO
  • AmeriGEOSS
  • CKAN
  • GEO
  • GEOSS
  • National
  • North America
  • United States
  • animal-and-tissue-sampling
  • animal-husbandry
  • data-transformation
  • dissection-condition
  • dna-library-construction
  • epitranscriptomics
  • extraction
  • genelab-rnaseq-data-processing-protocol
  • histology
  • labeling
  • library-construction
  • mass-spectrometry
  • mass-spectrometry-protocol
  • mouse-habitation
  • nucleic-acid-extraction
  • nucleic-acid-sequencing
  • protein-extraction
  • proteomics-data-transformation
  • rna-sequencing-library-construction
  • sample-collection
  • spaceflight
  • tmt-isobaric-labeling
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license_id us-pd
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maintainer GeneLab Outreach
maintainer_email genelab-outreach@lists.nasa.gov
metadata_created 2025-09-23T18:48:35.416725
metadata_modified 2025-09-23T18:48:35.416731
notes RR-1 is a validation flight to evaluate the hardware operational and science capabilities of the Rodent Research Project on the ISS. RNA DNA and protein were purified from liver tissues from RR-1 mice (female C57BL/6J 16wk old at time of launch). From each group two liver samples were collected and frozen immediately after euthanasia. The rest of the liver samples from each group were collected from frozen carcasses dissected post-flight. RNA-Seq whole genome and RNA BS-Seq (bisulfite sequencing) and proteomic expression profiling were performed. RNA extracted from these tissues was re-sequenced; these data are available as part of GLDS-168 (https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-168).
num_resources 1
num_tags 31
title Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic proteomic and epigenomic data