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The CompTox Chemistry Dashboard: a community data resource for environmental...
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the... -
Evaluation of food-relevant chemicals in the ToxCast high-throughput...
Thousands of chemicals are directly added to or come in contact with food, many of which have undergone little to no toxicological evaluation. The landscape of the food-relevant... -
Aggregated Computational Toxicology Online Resource
Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from over 1,000... -
SEQUENCING AND DE NOVO DRAFT ASSEMBLIES OF A FATHEAD MINNOW (Pimpehales...
The dataset provides the URLs for accessing the genome sequence data and two draft assemblies as well as fathead minnow genotyping data associated with estimating the... -
Chemical-Gene and Chemical-Pathway Interactions Predicted for Chemicals...
Data from study assessing the utility of knowledgebase-leveraging of comprehensive environmental-contaminant-exposure datasets by comparing biological effects predicted on the... -
Chemical-Gene and Chemical-Pathway Interactions Predicted for Chemicals...
Data from study assessing the utility of knowledgebase-leveraging of comprehensive environmental-contaminant-exposure datasets by comparing biological effects predicted on the... -
Concentrations of Pharmaceutical Contaminants and Their Predicted Effects...
Human-use pharmaceutical compounds were analyzed at the U.S. Geological Survey, National Water Quality Laboratory, Denver, Colorado, in wadeable streams in 4 Regional Stream... -
Concentrations of Pharmaceutical Contaminants and Their Predicted Effects...
Human-use pharmaceutical compounds were analyzed at the U.S. Geological Survey, National Water Quality Laboratory, Denver, Colorado, in wadeable streams in 4 Regional Stream... -
Pilot testing and optimization of a larval fathead minnow high throughput...
The present study describes pilot testing of a high throughput compatible transcriptomics assay with larval fathead minnows. One day post hatch fathead minnows were exposed to... -
Exposure Forecaster
The Exposure Forecaster Database (ExpoCastDB) is EPA's database for aggregating chemical exposure information and can be used to help with chemical exposure predictions. The... -
Bioactivity screening of environmental chemicals using imaging-based...
In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics capabilities for... -
SSDn insecticide dataset
This is a dataset of acute toxicity values for organophosphate and carbamate insecticides. the dataset is used to develop and validate the species sensitivity distribution... -
Dataset for 'Signature Analysis of High-Throughput Transcriptomics Screening...
Dataset for Harrill, J.A. et al., 'Signature Analysis of High-Throughput Transcriptomics Screening Data for Mechanistic Inference and Chemical Grouping' published in... -
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay...
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-... -
High-throughput screening of chemical effects on steroidogenesis using H295R...
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay... -
Concentrations of Pesticides, Pharmaceuticals, Organic Waste Indicators, and...
This dataset presents the results of 475 unique organic compounds collected from 54 wadeable streams within the Southeastern, USA, collected within 10 weeks during 2014. Maximum... -
Interactive Chemical Safety for Sustainablity Toxicity Forecaster Dashboard
EPA researchers have been using advances in computational toxicology to address lack of data on the thousands of chemicals. EPA released chemical data on 1,800 chemicals. The...