Dataset for "Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid'

These spreadsheets contain the underlying data, calculations, and R code for the figures of the manuscript "Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid". The first tab of every spreadsheet contains descriptions of the data (metadata). For clarifying questions regarding the data, please contact Dr. Brian Chorley (EPA-ORD) at chorley.brian@epa.gov. If you require a review token for the sequencing datasets located in the GEO links (RNAseq and RRBS), please contact Dr. Chorley.

This dataset is associated with the following publication: Carswell, G., J. Chamberlin, B. Bennett, P. Bushel, and B. Chorley. Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid. Frontiers in Oncology. Frontiers, Lausanne, SWITZERLAND, 14: 1389634, (2024).

Data and Resources

Field Value
accessLevel public
bureauCode {020:00}
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
identifier https://doi.org/10.23719/1529544
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2023-09-08
programCode {020:000}
publisher U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
references {https://doi.org/10.3389/fonc.2024.1389634,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11099211}
resource-type Dataset
source_datajson_identifier true
source_hash b3b9fa7fc10ebb6e09196f98f84a8d7f8d7a528efbcf510cf7915112569adde9
source_schema_version 1.1
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • AmeriGEO
  • AmeriGEOSS
  • CKAN
  • GEO
  • GEOSS
  • National
  • North America
  • United States
  • archival-samples
  • dichloroacetic-acid
  • dna-methylation
  • liver-cancer
  • transcriptomics
isopen False
license_id other-license-specified
license_title other-license-specified
maintainer Brian Chorley
maintainer_email chorley.brian@epa.gov
metadata_created 2025-09-24T11:18:39.440077
metadata_modified 2025-09-24T11:18:39.440087
notes These spreadsheets contain the underlying data, calculations, and R code for the figures of the manuscript "Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid". The first tab of every spreadsheet contains descriptions of the data (metadata). For clarifying questions regarding the data, please contact Dr. Brian Chorley (EPA-ORD) at chorley.brian@epa.gov. If you require a review token for the sequencing datasets located in the GEO links (RNAseq and RRBS), please contact Dr. Chorley. This dataset is associated with the following publication: Carswell, G., J. Chamberlin, B. Bennett, P. Bushel, and B. Chorley. Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid. Frontiers in Oncology. Frontiers, Lausanne, SWITZERLAND, 14: 1389634, (2024).
num_resources 10
num_tags 13
title Dataset for "Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid'