Gene Expression Profile Changes due to Bleomycin-Induced DNA Damage in Human Fibroblasts in Space

To understand gene expression responses in confluent human fibroblast in microgravity conditions to bleomycin treatment. Confluent human fibroblasts AG01522 were flown to the International Space Station (ISS). After three day on ISS the cells were treated with bleomycin at 1.0 microg/ml for 3 hours. The cells were washed and fixed with RNALater. Total RNA were isolated after the samples were returned to earth and subject to microarray analysis.

Data and Resources

Field Value
accessLevel public
accrualPeriodicity irregular
bureauCode {026:00}
catalog_@context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
catalog_@id https://data.nasa.gov/data.json
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
catalog_describedBy https://project-open-data.cio.gov/v1.1/schema/catalog.json
identifier nasa_genelab_GLDS-114
issued 2018-06-26
landingPage https://data.nasa.gov/d/8s9g-2hsd
modified 2020-01-29
programCode {026:005}
publisher National Aeronautics and Space Administration
resource-type Dataset
source_datajson_identifier true
source_hash 73385c5a8142b20051b7037ba67e9efa48a1e9bc
source_schema_version 1.1
theme {"Earth Science"}
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • amerigeo
  • amerigeoss
  • bleomycin-treatment
  • ckan
  • data-collection
  • geo
  • geoss
  • labeling
  • microgravity
  • national
  • normalization-data-transformation
  • north-america
  • nucleic-acid-hybridization
  • rna-extraction
  • sample-collection
  • united-states
isopen False
license_id notspecified
license_title License not specified
maintainer GeneLab Outreach
maintainer_email genelab-outreach@lists.nasa.gov
metadata_created 2025-11-21T08:56:16.220342
metadata_modified 2025-11-21T08:56:16.220346
notes To understand gene expression responses in confluent human fibroblast in microgravity conditions to bleomycin treatment. Confluent human fibroblasts AG01522 were flown to the International Space Station (ISS). After three day on ISS the cells were treated with bleomycin at 1.0 microg/ml for 3 hours. The cells were washed and fixed with RNALater. Total RNA were isolated after the samples were returned to earth and subject to microarray analysis.
num_resources 1
num_tags 16
title Gene Expression Profile Changes due to Bleomycin-Induced DNA Damage in Human Fibroblasts in Space