Hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low birthweight, and hepatomegaly in the Sprague-Dawley rat Dataset

Complete summary data (mean, error, sample size) for all figures and tables associated with the present manuscript, which characterizes maternal, fetal, and neonatal effects of oral exposure to HFPO-DA (GenX) during gestation in the Sprague-Dawley rat .

This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, J. McCord, M. Strynar, D. Hill, E. MedlockKakaley, V. Wilson, and E. Gray. Hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low birthweight and hepatomegaly in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 146: 106204, (2021).

Data and Resources

Field Value
accessLevel public
bureauCode {020:00}
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
describedBy https://pasteur.epa.gov/uploads/10.23719/1520445/documents/ConleyJustin_A-x3gb_Dataset_Dictionary_20201102.docx
describedByType application/vnd.openxmlformats-officedocument.wordprocessingml.document
identifier https://doi.org/10.23719/1520445
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2020-11-02
programCode {020:095}
publisher U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
references {https://doi.org/10.1016/j.envint.2020.106204}
resource-type Dataset
source_datajson_identifier true
source_hash a4a2bf7193893d7f771853a61a6eb0df572f5920
source_schema_version 1.1
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • amerigeo
  • amerigeoss
  • ckan
  • developmental-toxicity
  • genx
  • geo
  • geoss
  • hfpo-da
  • national
  • north-america
  • polyfluorinated-alkyl-substances-pfas
  • united-states
isopen False
license_id other-license-specified
license_title other-license-specified
maintainer Justin Conley
maintainer_email conley.justin@epa.gov
metadata_created 2025-11-19T14:40:30.570891
metadata_modified 2025-11-19T14:40:30.570897
notes Complete summary data (mean, error, sample size) for all figures and tables associated with the present manuscript, which characterizes maternal, fetal, and neonatal effects of oral exposure to HFPO-DA (GenX) during gestation in the Sprague-Dawley rat . This dataset is associated with the following publication: Conley, J., C. Lambright, N. Evans, J. McCord, M. Strynar, D. Hill, E. MedlockKakaley, V. Wilson, and E. Gray. Hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low birthweight and hepatomegaly in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 146: 106204, (2021).
num_resources 1
num_tags 12
title Hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low birthweight, and hepatomegaly in the Sprague-Dawley rat Dataset