Rodent Research-3-CASIS: Mouse kidney transcriptomic proteomic and epigenomic data

The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the effectiveness of a potential countermeasure for the loss of muscle and bone mass that occurs during spaceflight. Twenty BALB/c 18-weeks old female mice (ten controls and ten treated) were flown to the ISS and housed in the AEM-X habitat for 39-42 days. Twenty mice of similar age sex and strain were used for ground controls housed in identical hardware and matching ISS environmental conditions. Basal controls were housed in standard vivarium cages. Spaceflight ground controls and basal groups had blood collected then were euthanized had one hind limb removed and finally whole carcasses were stored at -80 C until dissection. All mice in this data set received only the control/sham injection.

Data and Resources

Field Value
accessLevel public
accrualPeriodicity irregular
bureauCode {026:00}
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catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
catalog_describedBy https://project-open-data.cio.gov/v1.1/schema/catalog.json
identifier nasa_genelab_GLDS-163
issued 2018-06-26
landingPage https://data.nasa.gov/dataset/rodent-research-3-casis-mouse-kidney-transcriptomic-proteomic-and-epigenomic-data
modified 2025-04-23
programCode {026:005}
publisher National Aeronautics and Space Administration
resource-type Dataset
source_datajson_identifier true
source_hash dde6f584e3e296597ee115010fca26921ff57cb0f8992c8d6343738e5e38718e
source_schema_version 1.1
theme {"Earth Science"}
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • AmeriGEO
  • AmeriGEOSS
  • CKAN
  • GEO
  • GEOSS
  • National
  • North America
  • United States
  • data-transformation
  • labeling
  • library-construction
  • mass-spectrometry
  • microgravity
  • nucleic-acid-extraction
  • nucleic-acid-sequencing
  • protein-extraction
  • sample-collection
  • spike-in-control
  • spike-in-control-protocol
  • treatment
isopen False
license_id notspecified
license_title License not specified
maintainer GeneLab Outreach
maintainer_email genelab-outreach@lists.nasa.gov
metadata_created 2025-09-29T14:55:44.869378
metadata_modified 2025-09-29T14:55:44.869383
notes The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the effectiveness of a potential countermeasure for the loss of muscle and bone mass that occurs during spaceflight. Twenty BALB/c 18-weeks old female mice (ten controls and ten treated) were flown to the ISS and housed in the AEM-X habitat for 39-42 days. Twenty mice of similar age sex and strain were used for ground controls housed in identical hardware and matching ISS environmental conditions. Basal controls were housed in standard vivarium cages. Spaceflight ground controls and basal groups had blood collected then were euthanized had one hind limb removed and finally whole carcasses were stored at -80 C until dissection. All mice in this data set received only the control/sham injection.
num_resources 1
num_tags 20
title Rodent Research-3-CASIS: Mouse kidney transcriptomic proteomic and epigenomic data