Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic data

The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the effectiveness of a potential countermeasure for the loss of muscle and bone mass that occurs during spaceflight. Twenty BALB/c 18-weeks old female mice (ten controls and ten treated) were flown to the ISS and housed in the AEM-X habitat for 39-42 days. Twenty mice of similar age sex and strain were used for ground controls housed in identical hardware and matching ISS environmental conditions. Basal controls were housed in standard vivarium cages. Spaceflight ground controls and basal groups had blood collected then were euthanized had one hind limb removed and finally whole carcasses were stored at -80 C until dissection. All mice in this data set received only the control/sham injection.

Data and Resources

Field Value
accessLevel public
accrualPeriodicity irregular
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identifier nasa_genelab_GLDS-137
issued 2018-06-26
landingPage https://data.nasa.gov/d/mema-k6hv
modified 2020-01-29
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publisher National Aeronautics and Space Administration
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Groups
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  • National Provider
  • North America
Tags
  • amerigeo
  • amerigeoss
  • ckan
  • data-transformation
  • geo
  • geoss
  • labeling
  • library-construction
  • mass-spectrometry
  • microgravity
  • national
  • north-america
  • nucleic-acid-extraction
  • nucleic-acid-sequencing
  • protein-extraction
  • sample-collection
  • treatment
  • united-states
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license_title License not specified
maintainer GeneLab Outreach
maintainer_email genelab-outreach@lists.nasa.gov
metadata_created 2025-11-22T10:31:26.782432
metadata_modified 2025-11-22T10:31:26.782436
notes The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the effectiveness of a potential countermeasure for the loss of muscle and bone mass that occurs during spaceflight. Twenty BALB/c 18-weeks old female mice (ten controls and ten treated) were flown to the ISS and housed in the AEM-X habitat for 39-42 days. Twenty mice of similar age sex and strain were used for ground controls housed in identical hardware and matching ISS environmental conditions. Basal controls were housed in standard vivarium cages. Spaceflight ground controls and basal groups had blood collected then were euthanized had one hind limb removed and finally whole carcasses were stored at -80 C until dissection. All mice in this data set received only the control/sham injection.
num_resources 1
num_tags 18
title Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic data