Rodent Research-3-CASIS: Mouse retina transcriptomic data

The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the effectiveness of a potential countermeasure for the loss of muscle and bone mass that occurs during spaceflight. Twenty BALB/c 18-weeks old female mice (ten controls and ten treated) were flown to the ISS and housed in the Rodent Habitat for 39-42 days. Twenty mice of similar age sex and strain were used for ground controls housed in identical hardware and matching ISS environmental conditions. Basal controls were housed in standard vivarium cages. Spaceflight ground controls and basal groups had blood collected then were euthanized had one hind limb removed and finally whole carcasses were stored at -80 C until dissection. All mice in this data set received only the control/sham injection. Microdissection of retinae from previously frozen eyes and RNA isolation were performed in the laboratory of Dr. Xiao Mao at Loma Linda University.

Data and Resources

Field Value
accessLevel public
accrualPeriodicity irregular
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identifier nasa_genelab_GLDS-194
issued 2018-09-05
landingPage https://data.nasa.gov/d/4sw4-46nz
modified 2020-01-29
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publisher National Aeronautics and Space Administration
resource-type Dataset
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Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • amerigeo
  • amerigeoss
  • animal-husbandry
  • ckan
  • geo
  • geoss
  • library-construction
  • mouse-habitat
  • national
  • north-america
  • nucleic-acid-extraction
  • nucleic-acid-sequencing
  • nucleic-acid-sequencing-protocol
  • rna-sequencing-library-construction
  • sample-collection
  • spaceflight
  • spike-in-control
  • spike-in-quality-control-role
  • treatment
  • united-states
isopen False
license_id notspecified
license_title License not specified
maintainer GeneLab Outreach
maintainer_email genelab-outreach@lists.nasa.gov
metadata_created 2025-11-20T02:33:00.130368
metadata_modified 2025-11-20T02:33:00.130372
notes The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the effectiveness of a potential countermeasure for the loss of muscle and bone mass that occurs during spaceflight. Twenty BALB/c 18-weeks old female mice (ten controls and ten treated) were flown to the ISS and housed in the Rodent Habitat for 39-42 days. Twenty mice of similar age sex and strain were used for ground controls housed in identical hardware and matching ISS environmental conditions. Basal controls were housed in standard vivarium cages. Spaceflight ground controls and basal groups had blood collected then were euthanized had one hind limb removed and finally whole carcasses were stored at -80 C until dissection. All mice in this data set received only the control/sham injection. Microdissection of retinae from previously frozen eyes and RNA isolation were performed in the laboratory of Dr. Xiao Mao at Loma Linda University.
num_resources 1
num_tags 20
title Rodent Research-3-CASIS: Mouse retina transcriptomic data