Tox21BodyMap: A webtool to map chemical effects on the human body

This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body, facilitating predictions between chemical exposure and apical effects. Tox21BodyMap maps chemical effects to biological target tissues uses tissue-specific gene expression and high throughput screening data. High throughput screening sources includes ToxCast and Tox21. Tox21BodyMap is a freely available, online tool.

This dataset is associated with the following publication: Borrel, A., S. Auerbach, K. Houck, and N. Kleinstreuer. Tox21BodyMap: A webtool to map chemical effects on the human body. NUCLEIC ACIDS RESEARCH. Oxford University Press, Cary, NC, USA, 48(W1): W472-W476, (2020).

Data and Resources

Field Value
accessLevel public
bureauCode {020:00}
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
identifier https://doi.org/10.23719/1518701
license https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html
modified 2020-04-06
programCode {020:095}
publisher U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
references {https://doi.org/10.1093/nar/gkaa433}
resource-type Dataset
source_datajson_identifier true
source_hash b22bf4a620e8f7de9bdf581f84c4b42fbf7a6830
source_schema_version 1.1
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • amerigeo
  • amerigeoss
  • ckan
  • data-visualization
  • geo
  • geoss
  • high-throughput-screening-assay
  • national
  • north-america
  • tox21
  • tox21bodymap
  • toxcast
  • united-states
isopen False
license_id other-license-specified
license_title other-license-specified
maintainer Keith Houck
maintainer_email houck.keith@epa.gov
metadata_created 2025-11-21T04:02:53.602786
metadata_modified 2025-11-21T04:02:53.602790
notes This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body, facilitating predictions between chemical exposure and apical effects. Tox21BodyMap maps chemical effects to biological target tissues uses tissue-specific gene expression and high throughput screening data. High throughput screening sources includes ToxCast and Tox21. Tox21BodyMap is a freely available, online tool. This dataset is associated with the following publication: Borrel, A., S. Auerbach, K. Houck, and N. Kleinstreuer. Tox21BodyMap: A webtool to map chemical effects on the human body. NUCLEIC ACIDS RESEARCH. Oxford University Press, Cary, NC, USA, 48(W1): W472-W476, (2020).
num_resources 1
num_tags 13
title Tox21BodyMap: A webtool to map chemical effects on the human body