Triclosan Hershberger H295 data

Triclosan data from Hershberger experiment using castrated male rats. Data includes accessory sex tissue mean weights and thyroid gland weight following exposure to triclosan for 10 days both with and without testosterone stimulation. Also included are the thyroxine hormone means in these males. In addition, mean data on the in vitro adrenocortical cells for steroid hormone production (testosterone and estradiol) with a dose response of triclosan.

This dataset is associated with the following publication: Farmer, W., G. Louis, A. Buckalew, D. Hallinger, and T. Stoker. Evaluation of Triclosan in the Hershberger and H295R Steroidogenesis Assays. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, USA, 194-199, (2018).

Data and Resources

Field Value
accessLevel public
bureauCode {020:00}
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
identifier https://doi.org/10.23719/1407648
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2017-09-25
programCode {020:095}
publisher U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
references {https://doi.org/10.1016/j.toxlet.2018.03.001}
resource-type Dataset
source_datajson_identifier true
source_hash d395eacecf809504820661e52eb45fab990f0a81
source_schema_version 1.1
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • amerigeo
  • amerigeoss
  • androgen
  • ckan
  • endocrine
  • estrogen
  • geo
  • geoss
  • hershberger
  • national
  • north-america
  • steroids
  • thryoid-hormone
  • triclosan
  • united-states
isopen False
license_id other-license-specified
license_title other-license-specified
maintainer Tammy Stoker
maintainer_email stoker.tammy@epa.gov
metadata_created 2025-11-21T13:01:45.920339
metadata_modified 2025-11-21T13:01:45.920343
notes Triclosan data from Hershberger experiment using castrated male rats. Data includes accessory sex tissue mean weights and thyroid gland weight following exposure to triclosan for 10 days both with and without testosterone stimulation. Also included are the thyroxine hormone means in these males. In addition, mean data on the in vitro adrenocortical cells for steroid hormone production (testosterone and estradiol) with a dose response of triclosan. This dataset is associated with the following publication: Farmer, W., G. Louis, A. Buckalew, D. Hallinger, and T. Stoker. Evaluation of Triclosan in the Hershberger and H295R Steroidogenesis Assays. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, USA, 194-199, (2018).
num_resources 1
num_tags 15
title Triclosan Hershberger H295 data