Using Targeted Fetal Rat Testis Genomic and Endocrine Alterations to Predict the Effects of a Phthalate Mixture on the Male Reproductive Tract.
Data and Resources
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DBP DINP MIX paper METADATA FOR PUBLICATION.xlsXLS
DBP%20DINP%20MIX%20paper%20METADATA%20FOR%20PUBLICATION.xls
| Field | Value |
|---|---|
| accessLevel | public |
| bureauCode | {020:00} |
| catalog_conformsTo | https://project-open-data.cio.gov/v1.1/schema |
| identifier | https://doi.org/10.23719/1530554 |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2024-03-27 |
| programCode | {020:000} |
| publisher | U.S. EPA Office of Research and Development (ORD) |
| publisher_hierarchy | U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD) |
| references | {https://doi.org/10.1016/j.crtox.2024.100180,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239482} |
| resource-type | Dataset |
| source_datajson_identifier | true |
| source_hash | f845aa92f900327720a47a466137cbfad7bf709fd2698da5a9d64c2ca9d62eed |
| source_schema_version | 1.1 |
| Groups |
|
| Tags |
|
| isopen | False |
| license_id | other-license-specified |
| license_title | other-license-specified |
| maintainer | Leon Gray |
| maintainer_email | gray.earl@epa.gov |
| metadata_created | 2025-09-24T00:46:00.432242 |
| metadata_modified | 2025-09-24T00:46:00.432251 |
| notes | METADATA OUTLINE SHEET 1 STUDY INFORMATION SHEET 2 RANDOM ASSISNMENT OF PREGNANT RATS TO TREATMENT GROUPS SHEER 3 MATERNAL WEIGHT AND WEIGHT GAIN DURING DOSING and fetal DATA RAW DATA RESULTS PREDICTIONS OF DOSE ADDITIVITY SHEET 4 TESTOSTERONE (T PROD) DATA RAW DATA SAS INPUT FILES TREATMENT EFFECTS SHEET 5 CUSTOM GENE (mRNA) SAS INPUT FILE WITH SAS STATEMENTS AND RQW DATA SHEET 6 RESULTS FROM STATISTICAL ANALYSIS OF CUSTOM ARRAY mRNA DATA CUSTOM ARRAY: LIST OF GENES AND GENE DESCRIPTIONS SHEET 7 PREDICTION MODELS OF TESTOSTERONE PRODUCTION REDUCTIONS AND REPRODUCTIVE EFFECTS OF IN UTERO PHTHALATE EXPOSURE SHEET 8 TREATMENT EFFECTS PREDICTED FROM THE TESTOSTERONE PREDICTION MODELS COMPARISON OF THE PREDICTED EFFECTS OF THE DBP+DINP MIXTURE WITH OBSERVED EFFECTS OF THE REFERENCE CHEMICAL (DBP) AT EQUIVALENT DOSES, ASSUMING DOSE ADDITIVITY. This dataset is associated with the following publication: Gray, L., C. Lambright, N. Evans, J. Ford, and J. Conley. Using Targeted Fetal Rat Testis Genomic and Endocrine Alterations to Predict the Effects of a Phthalate Mixture on the Male Reproductive Tract.. Current Research in Toxicology. Elsevier B.V., Amsterdam, NETHERLANDS, 7: 100180, (2024). |
| num_resources | 1 |
| num_tags | 9 |
| title | Using Targeted Fetal Rat Testis Genomic and Endocrine Alterations to Predict the Effects of a Phthalate Mixture on the Male Reproductive Tract. |