PFBS tissue concentrations and liver gene expression in mice

File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for nuclear receptors at 24 h post-treatment.

This dataset is associated with the following publication: Lau, C., J. Rumpler, K. Das, C. Wood, J. Schmid, M. Strynar, and J. Wambaugh. Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441: 152522, (2020).

Data and Resources

Field Value
accessLevel public
bureauCode {020:00}
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
identifier https://doi.org/10.23719/1519339
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2020-09-14
programCode {020:000}
publisher U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
references {https://doi.org/10.1016/j.tox.2020.152522}
resource-type Dataset
source_datajson_identifier true
source_hash 1a493c326615270f6a3e81c61f948d8244d8e915
source_schema_version 1.1
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • amerigeo
  • amerigeoss
  • chemical-contaminant
  • ckan
  • geo
  • geoss
  • national
  • north-america
  • pfbs
  • pharmacokinetics
  • transcriptomics
  • united-states
isopen False
license_id other-license-specified
license_title other-license-specified
maintainer Christopher Lau
maintainer_email lau.christopher@epa.gov
metadata_created 2025-11-22T17:25:31.198212
metadata_modified 2025-11-22T17:25:31.198216
notes File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for nuclear receptors at 24 h post-treatment. This dataset is associated with the following publication: Lau, C., J. Rumpler, K. Das, C. Wood, J. Schmid, M. Strynar, and J. Wambaugh. Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice. TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 441: 152522, (2020).
num_resources 1
num_tags 12
title PFBS tissue concentrations and liver gene expression in mice