in vitro and microsome experiment data

exposure_experiment.csv: time: length of time that amphibian was exposed to that pesticide in hours.
parent: is the active ingredient that the amphibian was exposed to.
analyte: either the main parent compound or the metabolite that was quantified.
matrix: the sample that was analyzed either the amphibian or soil.
conc: is the concentration for that specific analyte in that matrix for that specific species in microg/g replicate: is the individual amphibian or soil exposed to that pesticide.

microsome_experiment3.csv:
time: is the length of time that the microsomes were exposed before being quenched in minutes.
parent: is the active ingredient that the amphibian was exposed to.
analyte: either the main parent compound or the metabolite that was quantified.
matrix: the sample that was analyzed microsomes.
conc: is the concentration for that specific analyte in that matrix for that specific species. in micromolar (uM) replicate: is the individual microsome exposed to that pesticide. microMexp: is the concentration in micromolar (uM) that the microsomes were exposed to for that pesticide.

This dataset is associated with the following publication: Glinski, D., M. Henderson, R. Van Meter, and T. Purucker. Using in vitro derived enzymatic reaction rates of metabolism to inform pesticide body burdens in amphibians. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, USA, 288: 9-16, (2018).

Data e Risorse

Campo Valore
accessLevel public
bureauCode {020:00}
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
identifier https://doi.org/10.23719/1407588
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2017-04-12
programCode {020:095}
publisher U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
references {https://doi.org/10.1016/j.toxlet.2018.02.016}
resource-type Dataset
source_datajson_identifier true
source_hash ab446b3581f4a726d29c946a365c43b25a8925bb
source_schema_version 1.1
Gruppi
  • AmeriGEOSS
  • National Provider
  • North America
Tag
  • amerigeo
  • amerigeoss
  • amphibians
  • ckan
  • geo
  • geoss
  • metabolism
  • microsomes
  • national
  • north-america
  • pesticides
  • united-states
isopen False
license_id other-license-specified
license_title other-license-specified
maintainer Steven Purucker
maintainer_email purucker.tom@epa.gov
metadata_created 2025-11-22T23:34:10.887435
metadata_modified 2025-11-22T23:34:10.887438
notes exposure_experiment.csv: time: length of time that amphibian was exposed to that pesticide in hours. parent: is the active ingredient that the amphibian was exposed to. analyte: either the main parent compound or the metabolite that was quantified. matrix: the sample that was analyzed either the amphibian or soil. conc: is the concentration for that specific analyte in that matrix for that specific species in microg/g replicate: is the individual amphibian or soil exposed to that pesticide. microsome_experiment3.csv: time: is the length of time that the microsomes were exposed before being quenched in minutes. parent: is the active ingredient that the amphibian was exposed to. analyte: either the main parent compound or the metabolite that was quantified. matrix: the sample that was analyzed microsomes. conc: is the concentration for that specific analyte in that matrix for that specific species. in micromolar (uM) replicate: is the individual microsome exposed to that pesticide. microMexp: is the concentration in micromolar (uM) that the microsomes were exposed to for that pesticide. This dataset is associated with the following publication: Glinski, D., M. Henderson, R. Van Meter, and T. Purucker. Using in vitro derived enzymatic reaction rates of metabolism to inform pesticide body burdens in amphibians. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, USA, 288: 9-16, (2018).
num_resources 1
num_tags 12
title in vitro and microsome experiment data