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Respirometric Screening and Characterization of Mitochondrial Toxicants Withi...
These are the raw data files for TOXSCI manuscript 19-0578 entitled, “Respirometric Screening and Characterization of Mitochondrial Toxicants Within the ToxCast Phase I and II... -
Evaluation of food-relevant chemicals in the ToxCast high-throughput screenin...
Thousands of chemicals are directly added to or come in contact with food, many of which have undergone little to no toxicological evaluation. The landscape of the food-relevant... -
Predict_Organ_Toxicity_ChemResTox_Data
We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor on... -
KPF_Examining the Utility of In Vitro Bioactivity as a Protective Point of De...
The files and .R scripts here are provided to aid in understanding and reproduction of the analyses in the submitted paper, "Examining the Utility of In Vitro Bioactivity as a... -
Quantitative Structure-Use Relationship Model Predictions to evaluate Tox21 C...
This dataset provides a prediction for all Tox21 chemicals with available QSUR descriptors across all 41 valid QSUR models developed with FUse. This dataset is associated with... -
MMartin_DFiler_tcpl: the ToxCast pipeline for high-throughput screening data
The tcpl package provides a set of tools for processing and modeling high-throughput and high-content chemical screening data. This dataset is associated with the following... -
Selecting a Minimal set of Androgen Receptor Assays for Screening Chemicals
Screening certain environmental chemicals for their ability to interact with endocrine targets, including the androgen receptor (AR), is an important global concern. We... -
Dataset for ORD-033294: Mining a human transcriptome database for chemical mo...
Gene Expression Omnibus and ArrayExpress archived study numbers of microarray data used in the study. This dataset is associated with the following publication: Rooney, J., B.... -
Dataset for 'Development of a bioprinter-based method for incorporating metab...
Data for Hopperstad K and Deisenroth C (2023) Development of a bioprinter-based method for incorporating metabolic competence into high-throughput in vitro assays. Front.... -
Targeted Per- and Polyfluoroalkyl Substances (PFAS) Assessments for High Thro...
Data for "Smeltz MG, Clifton MS, Henderson WM, McMillan L, Wetmore BA. Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening: Analytical... -
Dataset for journal article 'The DevTox Germ Layer Reporter Platform: An Assa...
The zip file enclosed contains README_Gamble_DevTox GLR_Sup Data_v1.docx, Gamble_DevTox GLR_Sup Fig_Submission_v1.docx, Gamble_DevTox GLR_Tables_Submission_v1.xlsx,... -
High-throughput AR dimerization assay identifies androgen disrupting chemical...
Repository for supplemental files and code for paper titled "High-throughput AR Dimerization Assay Identifies Androgen Disrupting Chemicals and Metabolites", 2022. This dataset... -
Prioritization of chemicals for effects on steroidogenesis using an integrate...
HT-H295R data was downloaded using the ToxCast pipeline (tcpl) R package and is publicly available. Multi-concentration level 0 data from invitrodb (version 3.1) were downloaded... -
Blog | Introducing Chemical Effects in Biological Systems (CEBS): a Database ...
This blog post was posted by Ellie Sheridan on July 29, 2016. -
Quantitative Structure-Use Relationship Model thresholds for Model Validation...
This file contains value of the model training set confusion matrix, domain of applicability evaluation based on training set to predicted chemicals structural similarity, and... -
Pesticide Prioritization by Potential Biological Effects in Tributaries of th...
Data files for "Oliver, S.K., Corsi, S.R., Baldwin, A.K., Nott, M.A., Ankley, G.T., Blackwell, B.R., Villeneuve, D.L., Hladik, M.L., Kolpin, D.W., Loken, L., DeCicco, L.A.,... -
Comparison of in silico, in vitro, and in vivo toxicity benchmarks suggests a...
Supplemental data for "Schaupp CM, Maloney EM, Mattingly K, Olker JH, Villeneuve DL. Comparison of in silico, in vitro, and in vivo toxicity benchmarks suggests a role for... -
A cross-platform approach to characterize and screen potential neurovascular ...
Development of the neurovascular unit (NVU) is a complex, multistage process that requires orchestrated cell signaling mechanisms across several cell types and ultimately... -
Limited chemical structural diversity found to modulate thyroid hormone recep...
The Tox21 chemical library (8,305 unique structures) was screened in a quantitative high-throughput, cell-based reporter gene assay for TR agonist or antagonist activity. Active... -
Screening silver nanoparticles for potential neurotoxicity using cortical neu...
the zip files contain outputs from the R-analysis for the nanosilver experiments. This dataset is associated with the following publication: Strickland, J., W. LeFew, J. Crooks,...