Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening

Dataset for 'Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening', Garnovskaya, et al., Toxicology in Vitro, Vol 92, 105659, Oct 2023, https://doi.org/10.1016/j.tiv.2023.105659. Contains the ToxCast Pipeline datasets and curve fits that can be pulled up from InvitroDB on the CompTox Chemicals Dashboard.

This dataset is associated with the following publication: Garnovskaya, M., M. Feshuk, W. Stewart, K. Friedman, R. Thomas, and C. Deisenroth. Evaluation of a High-throughput H295R Homogenous Time Resolved Fluorescence Assay for Androgen and Estrogen Steroidogenesis Screening. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 92: 105659, (2023).

Data and Resources

Field Value
accessLevel public
bureauCode {020:00}
catalog_conformsTo https://project-open-data.cio.gov/v1.1/schema
identifier https://doi.org/10.23719/1530103
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2022-08-08
programCode {020:000}
publisher U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
references {https://doi.org/10.1016/j.tiv.2023.105659}
resource-type Dataset
source_datajson_identifier true
source_hash 71c0c2f10c6966e8bab703af8decd062d45bbc80bde40d18878fa6cf9b496b12
source_schema_version 1.1
Groups
  • AmeriGEOSS
  • National Provider
  • North America
Tags
  • AmeriGEO
  • AmeriGEOSS
  • CKAN
  • GEO
  • GEOSS
  • National
  • North America
  • United States
  • androgen
  • endocrine-toxicology
  • estrogen
  • high-throughput-screening
  • new-approach-methods-alternatives-to-animal-testing
  • steroidogenesis
isopen False
license_id other-license-specified
license_title other-license-specified
maintainer Chad Deisenroth
maintainer_email deisenroth.chad@epa.gov
metadata_created 2025-09-23T17:13:29.218230
metadata_modified 2025-09-23T17:13:29.218237
notes Dataset for 'Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening', Garnovskaya, et al., Toxicology in Vitro, Vol 92, 105659, Oct 2023, https://doi.org/10.1016/j.tiv.2023.105659. Contains the ToxCast Pipeline datasets and curve fits that can be pulled up from InvitroDB on the CompTox Chemicals Dashboard. This dataset is associated with the following publication: Garnovskaya, M., M. Feshuk, W. Stewart, K. Friedman, R. Thomas, and C. Deisenroth. Evaluation of a High-throughput H295R Homogenous Time Resolved Fluorescence Assay for Androgen and Estrogen Steroidogenesis Screening. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 92: 105659, (2023).
num_resources 4
num_tags 14
title Evaluation of a high-throughput H295R homogenous time resolved fluorescence assay for androgen and estrogen steroidogenesis screening