Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant)

Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and microRNA microarray in dauer larvae of Caenorhabditis elegans (C. elegans) that endured space xef xac x82ight environment and space radiations environment during 16.5-day Shenzhou-8 space mission were performed. In our study wild type and ced-1 mutant strains of C.elegans endured three conditions during shenzhou-8 spaceflight mission including spaceflight static condition(ss) spaceflight 1-g centrifugal condition(sc) and ground control condition(gc). Limited to the quantity of worm samples we performed technical-repeat test but not sample-repeat test.Accordingly xef xbc x8csix miRNA microarrays were performed.

Data e Risorse

Campo Valore
accessLevel public
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identifier nasa_genelab_GLDS-166
issued 2018-06-26
landingPage https://data.nasa.gov/d/qesx-a6xb
modified 2020-01-29
programCode {026:005}
publisher National Aeronautics and Space Administration
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Gruppi
  • AmeriGEOSS
  • National Provider
  • North America
Tag
  • absorbed-radiation-dose
  • amerigeo
  • amerigeoss
  • ckan
  • data-collection
  • geo
  • geoss
  • labeling
  • national
  • normalization-data-transformation
  • north-america
  • nucleic-acid-hybridization
  • rna-extraction
  • sample-collection
  • united-states
  • weightlessness
isopen False
license_id notspecified
license_title License not specified
maintainer GeneLab Outreach
maintainer_email genelab-outreach@lists.nasa.gov
metadata_created 2025-11-21T00:05:33.215199
metadata_modified 2025-11-21T00:05:33.215203
notes Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA microarray and microRNA microarray in dauer larvae of Caenorhabditis elegans (C. elegans) that endured space xef xac x82ight environment and space radiations environment during 16.5-day Shenzhou-8 space mission were performed. In our study wild type and ced-1 mutant strains of C.elegans endured three conditions during shenzhou-8 spaceflight mission including spaceflight static condition(ss) spaceflight 1-g centrifugal condition(sc) and ground control condition(gc). Limited to the quantity of worm samples we performed technical-repeat test but not sample-repeat test.Accordingly xef xbc x8csix miRNA microarrays were performed.
num_resources 1
num_tags 16
title Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant)